After a 2016 CDC alert describing infections caused by the multidrug-resistant fungus Candida auris (1), the Colombian Instituto Nacional de Salud (INS) queried the country's WHONET † database of invasive Candida isolates to detect previous C. auris infections.No C. auris isolates were identified during 2012-2016.However, C. auris is often misidentified as Candida haemulonii (2), a yeast that rarely causes invasive infections, and 75 C. haemulonii isolates were reported during May 2013-August 2016.These isolates came primarily from patients in intensive care units in the country's north region, approximately 350-600 km (220-375 miles) from Maracaibo, Venezuela, where C. auris cases were first identified in 2012 (3).Of the 75 reported Colombian C. haemulonii isolates in WHONET, INS obtained 45 isolates from six medical institutions dating from February 2015 through August 2016, all of which were confirmed to be C. auris by matrix-assisted laser desorption ionization-time of flight (MALDI-TOF) mass spectrometry.Based on these findings, INS issued a national alert and mandated reporting of suspected isolates on August 30, 2016 § (3,4).In September 2016, a team from INS, CDC, and medical staff members from hospitals with documented C. auris cases investigated the 45 MALDI-TOF-confirmed C. auris cases identified before the INS alert.This investigation involved two hospitals in the north region and two in the central region.Cases were clustered within specific hospital units, and surveillance sampling demonstrated transmission in health care settings (INS and CDC, unpublished data, 2018).After release of the Colombian clinical alert, INS received suspected C. auris isolates for confirmatory testing, and during September 2016-May 2017, an additional 78 C. auris cases were identified from 24 health care facilities in nine states, resulting in a total of 123 confirmed C. auris cases (Figure), more than half (54.5%) recovered from the northern coastal * These authors contributed equally.