Pituitary carcinoma is considered as extremely rare neoplasm and account for 0.1%–0.2% pituitary neoplasm.[1] Pituitary carcinoma carry very poor prognosis. For confirmation of the diagnosis of pituitary carcinoma, require radiological as well histopathological demonstration of the presence of metastases. Pituitary carcinoma may develop due to malignant transformation of preexisting functional hormone secreting benign pituitary adenoma after a varying period of latency, which may extend up to many years after the initial diagnosis ranging from few months to many years. Present with extracranial metastasis. Authors report an interesting case with invasive prolactinoma, who presented with pathological fracture of femur. She underwent surgical management.