Sarcoidosis is a multisystemic, granulomatous disease with particular involvement in the lungs and the intrathoracic lymph nodes.Pleural fluid has been reported to occur in 0% to 5% of the cases in the literature.Diagnosis depends on the presence of noncaseating granulomas in the biopsy sample and the exclusion of other possibilities.A 77-year-old woman with complaints of shortness of breath and a dry cough was found to have non-necrotizing granulomatous inflammation in pleural biopsy and computed tomography guided transthoracic Tru-Cut biopsy specimens.This was a rare case in which partial recovery was achieved through treatment with methylprednisolone for a year in reduced doses.