The present document is a reflection on the effects of the border closure on the northern border of Santander-Tachira from 2015 to 2016, from a flexible perspective, starting from the concept of Cross-Border Region related to the complex dynamics between Frontier-Fracture and Frontier- Sewing, these concepts are important to understand the disruptive processes that frame this territorial, economic, social and humanitarian context that has been negatively affected by the deterioration of social capital, and its implications for achieving a Border-Potentiality , Which is elusive, but also as a challenge and purpose necessary for the well-being of the citizens of this vital space.