This article describes the perceived conflict between family life and work life, the relationship between the practices of work-family balance and the conciliation needs of administrative employees at the University of Antioquia, considering two theoretical lines: work-family conflict and work-family conciliation from the perspective of corporate family responsibility. This descriptive study used qualitative and quantitative methods. As a relevant result, there was evidence of work-family conflict related to how work schedules and stress interfere with family life. However, it was demonstrated that the institution implements practices perceived by employees to minimize the effects on the level of work-family conflict. The employees recognize 61 conciliation practices related to flexible work arrangements, professional care, and family and fringe benefits services. Additionally, emerging elements were identified that influence the perception of conflict.