AIMTo investigate the incidence of disadvantageous events by using the Global Trigger Tool in an intensive care unit (ICU). METHODSA retrospective descriptive study was performed in a 12-bed university ICU in the city of Medellin, Colombia.Clinical charts of hospitalized patients were reviewed, between January 1 and December 31, 2016, with the following inclusion criteria: subjects aged over 18 years, with at least 24 h of hospitalization and who had a complete medical history that could be accessed.Interventions: Trained reviewers conducted a retrospective examination of medical charts searching for clue events that elicit investigation, in order to detect an unfavorable event.Measurements