<b>Introduction and objectives:</b> Asthma affects up to 20% of the general population. Severe asthma (SA) accounts for 10 to 15% of them, but causes the highest impact to patients and health system. Our aim was to characterize children with SA treated at the Fundación Neumológica Colombiana because of there are not studies in Colombia about this condition. <b>Methods:</b> Observational, analytical, cross-sectional study in children between 6 and 15 years old, consecutively recruited, with SA diagnosed according to the American Thoracic Society criteria. Patients were subjected to asthma questionnaires (CASI and ACT), spirometry, skin prick tests (SPT), serum IgE and exhaled fraction of nitric oxide (FeNO). Association between variables was explored by Pearson or Spearman correlation coefficients depending on the normality of data. <b>Results:</b> Sixty children were included. Most patients were male (61.3%), median age of 10 years (Interquartile range –IQR- 8-12), median BMI 17 kg/m2 (IQR: 16-20). CASI (mean ±SD): 7.69 ±2.53; ACT: 20 ±4.13. Median of positive SPT: 2 (IQR: 2-3). At least one SPT was positive in 88.7% of patients and 87.9% were positive for mites. The median serum IgE was 348 UI/mL (IQR: 154-760) and the median FeNO was 22 ppb (IQR: 9-41). Prebronchodilator values were (% predicted): FVC: 109.7% (±15.5%), FEV1: 98.4% (±16.3); FEV1/FVC: 82% (±8%). SPT were correlated with the FEV1/FVC (Rho: -0.34; 95% CI: -0.55 a -0.09; P=0.008). FeNO was not significantly correlated with FEV1/FVC (Rho: -0.25; 95% CI: -0.52 a 0.06; P=0.10). Neither FeNO nor IgE were correlated with the CASI or the ACT. <b>Conclusions:</b> The established phenotype of SA for our population was allergic, non-obese children, with normal lung function and variable FeNO.