Pyrazolo[3,4-<italic>b</italic>]pyridines derivatives have been synthesized <italic>via</italic> one-pot condensation of 3-methyl-1-phenyl-1<italic>H</italic>-pyrazolo-5-amine (<bold>1</bold>), paraformaldehyde (<bold>2</bold>) and β-diketones (<bold>3</bold>) under microwave irradiation in aqueous media catalyzed by InCl₃.