Objective: The purpose of this study was the evaluation of an inter-cultural competence training program among first and sixth semester medical students at a university in Colombia. Materials and methods: This study utilized a quasi-experimental research design to evaluate an intercultural training program among 100 first and sixth semester medical students. Data were collected using the Intercultural Competency Scale and were analyzed using Wilcoxon Signal Range Test for related samples in SPSS version 21. Results: Significant differences were found in the areas of developing cultural sensitivity as well as developing understanding and respect for differences and diversity among first and six semester students in the experimental group Conclusions: Findings suggest a strong need to incorporate intercultural training into the educational experience of medical students.