The abundant use of emerging micro-pollutants and their inadequate final disposal have focused the attention of environmental authorities on the effects on the environment of antibacterial and antimicrobial agents discharged into bodies of water. Currently, several researches have focused their objectives on determining the efficiencies that different physical, chemical and biological treatments present to remove different pharmaceutical products including those mentioned above. This review includes results of various treatments at the microcosm, mesocosm and real scale level, which include the main experimental conditions in which the measurements are developed.