In this work was used a methodology for the magnetic simulation of power transformers for 12-pulse rectifiers. For the magnetic simulation of transformers the software ANSYS Maxwell was used, while for the model of circuits the software ANSYS Simplorer was used. Parameters such as electric losses in active components due to harmonics were analyzed. In final part of this work a comparison is made between results in simplified conditions compared with the realistic operation conditions of transformer connected to a 12-pulse rectifier.