El síndrome de Moebius es una enfermedad congénita caracterizada por parálisis facial no progresiva y alteración de la abducción ocular de uno o ambos ojos por compromiso del VI par, pudiendo extenderse a otros pares oculomotores, así como al IX, X y XII. Se ha asociado con manifestaciones musculoesqueléticas y epilepsia. Presentamos el caso de un preescolar con antecedente de intento fallido de la madre de interrupción voluntaria del embarazo en el primer trimestre. Al nacimiento se evidencia diplejía facial, parálisis bilateral del VI par y pie equino varo. A los 17 días de vida presenta crisis tónico-clónicas y se diagnostica síndrome de Moebius y epilepsia de difícil control. Durante el seguimiento presenta retardo global del desarrollo, con predominio en el área del lenguaje y alteración de la deglución. Moebius syndrome consists of congenital non-progressive facial nerve palsy and unilateral or bilateral paralysis of the sixth cranial nerve with inability to abduct the eye. The oculomotor cranial nerves, as well as, cranial nerves IX, X and XII, may also be affected. This syndrome has also been associated with anomalies of the musculoskeletal system and epilepsy. A case is presented in a preschool boy whose mother tried to voluntarily interrupt pregnancy in the first trimester but failed to abort. Facial diplegia, bilateral sixth cranial nerve palsy and bilateral equinovarus deformity of the feet were evidenced at birth. At 17 days of life he presented a tonic-clonic seizure and was diagnosed with Moebius syndrome and difficult to treat epilepsy. Delayed overall development, predominantly swallowing and speech difficulties, were evidenced upon follow up.