This essay explores the theoretical arguments regarding the existence of "smart" territories, a recently-developed concept based on notions related to the knowledge society and knowledge economy, sustainable development, and social inclusion. This paper examines the preconditions necessary to make it possible for this type of territorial development to emerge in relation to the economic development underpinning it, as well as the right type of social structure, qualities required for human agency, and the social innovations demanded for such purpose. Finally, as a case study, this paper provides an empirical analysis of such conditions on the Caribbean coast of Colombia, drawing some final conclusions and recommendations from it.