This article will analyze the normative challenge that Colombia has with signature of the Convention on the Rights of Persons with Disabilities on the subject as civil law, family law, criminal law, labor law and social security. This document explain it about different challenges the state Colombian to assume the commitments made with the signature and ratification especially with the generation of the legal guarantees; institutional policy and some changes of thinking in the legal professionals for recognize the rights about the legal capacity of people with disabilities.DOI: http://dx.doi.org/10.21615/cesder.8.1.1