Introduccion: la neurocisticercosis es una infeccion del sistema nervioso central causada por el parasito Taenia Solium, la parasitosis mas comun de este sistema y la principal causa de epilepsia adquirida. Objetivo: conocer cuales son las caracteristicas epidemiologicas y clinicas en una serie de ninos y adolescentes con diagnostico de neurocisticercosis. Metodologia: estudio retrospectivo, observacional, de historias clinicas, tipo serie de casos, de pacientes pediatricos con diagnostico de neurocisticercosis, evaluados y seguidos entre tres y diez meses en el Hospital Infantil Napoleon Franco Pareja, en Cartagena, Colombia, desde junio 2006 hasta junio 2011. Resultados: 201 historias clinicas fueron estudiadas, 112 (55.7%) de pacientes de procedencia rural y 89 (44.3%) urbana. Cuarenta casos nuevos anuales en promedio fueron observados en los ultimos cinco anos. Se revisaron varios casos en ninos por debajo de los dos anos de edad, lo cual es un comportamiento inusual. Todos los pacientes procedian del departamento de Bolivar en el Caribe colombiano. La poblacion estudiada pertenece a barrios urbanos y poblaciones rurales, que no cuentan con la infraestructura adecuada de servicios que garanticen un buen manejo de basuras y excretas. El sintoma clinico mas frecuente fue la crisis epileptica focal, seguido de las crisis epilepticas generalizadas y en tercer lugar el estatus convulsivo generalizado. Segun el estadio clinico, la enfermedad se presento de la siguiente manera: 29 (14.4%) tenian estadio clinico coloidal, 66 (32.8%) estadio clinico vesicular, 98 (48.8%) estadio clinico granular y 8 (4.0%) estadio clinico calcificado. En la gran mayoria de los casos (97.5%) se utilizo tratamiento antihelmintico. Control de las crisis epilepticas se consiguieron en el 100% de los casos. El 84.6% recibio un anticonvulsivante. En el seguimiento de los casos se identifico como primera secuela neurologica: la epilepsia adquirida (59%). Conclusion : la neurocisticercosis es una importante patologia que afecta desde edades tempranas, a ninos de zonas subnormales urbanas y rurales del Departamento de Bolivar, Colombia. Acciones preventivas, incluido mejoria en el saneamiento basico ambiental son indispensables. Rev.cienc.biomed. 2012;3(2): 217-225 PALABRAS CLAVES Cisticercosis; Neurocisticercosis; Epilepsia. SUMMARY Introduction: Neurocysticercosis is an infection of the central nervous system caused by the parasitic Taenia Solium, the most common parasites of this system and the principal cause of adquired epilepsy. Objective: To know which are the epidemiological and clinical characteristics in a series of children and adolescents with neurocysticercosis diagnosis. Methods: Retrospective, observational study of medical histories, case series type of pediatric patients with neurocysticercosis diagnosis that were evaluated and followed between three and ten months at Hospital Infantil Napoleon Franco Pareja, in Cartagena, Colombia, since June 2006 to June 2011. Results: 201 medical histories were studied, 112 (55.7%) were from rural areas and 89 (44.3%) were from urban areas. Fourty new cases per year on average were observed in the last five years. There were observed various cases in children of two years old or less, which is an unusual behavior. All patients were from Bolivar´s department in the Colombian Caribbean. The most frequent clinical symptom was focal epileptic crisis, fo­llowed by generalized epileptic crisis and in the third place, generalized convulsive status. The disease appeared of the following way according to the clinical stadium: 29 (14.4%) had colloidal clinical stadium, 66 (32.8%) vesicular clinical stadium, 98 (48.8%) granu­lar clinical stadium and 8 (4.0%) calcified clinical stadium. In the majority of the cases (97.5%) anthelmintic treatment was used. Epileptic crisis control was obtained in 100% of the cases. 84.6% received an anticolvulsivant. In the monitoring of the cases there was identified as the first neurologic consequence: The acquired epilepsy (59%). Studied population belongs to urban neighborhoods and rural populations, who don´t have an adequate infrastructure of services that guarantees a good management of garbage and output. Conclusion: Neurocysticercosis is an important disease that affects since early ages to children from subnormal urban and rural areas of Bolivar´s department. Preventive actions, included improvement in the environmental reorganization are indispensable. Rev.cienc.biomed. 2012;3(2): 217-225 KEYWORDS Cysticercosis; Neurocysticercosis; Epilepsy.