Cortical bone tissue is the responsible of giving support and structure to vertebrates.For that reason, understanding and analyzing its behavior is needed from each different hierarchical level that composes it.The lower the structural scale is, the greater the complexity and scarcity of studies in literature.These studies are relevant for understanding, preventing and solving important health problems that affect human beings.From a mechanical point of view is interesting to evaluate and apply engineering numerical tools to analyze complex materials as biological tissues, increasing the state of the art in different disciplines that can be applied in numerous fields as material science, biomechanics, numerical methods, medicine and more.