PURPOSE: To determine the relationship between physical condition and indirect indicators of cardiovascular risk students with intellectual disability Gustavo Restrepo College. METHODS: This is an observational study - analytical cross section. The study makes an assessment of the anthropometric profile and physical qualities, using battery Brockport Physical Fitness for children under 18; for over 18 years, the same tests were used but with rates for their age. A sample of 175 students were evaluated, of whom 96 were men and 79 women. For statistical analysis SPSS was used, using normality tests Kolmogorov-Smirnov and Pearson correlation. RESULTS: The results in body composition showed higher for the population over 18 years compared with under 18 values; variables related to physical abilities had higher results in over 18 years. For variables that obtained normality in the population under 18 years, the Pearson correlation was applied, with confidence levels of 95%, where it was observed that the anthropometric variables saved a correlation positive correlation between them, which you are setting a higher cardiovascular risk (R = 0.85, p 0.01). As for the correlation between anthropometric variables and variables of physical fitness as VO2max, and force variables, this correlation is negative (R = -0.365 p 0.01), showing that students evaluated with anthropometric overweight and obesity has values less physical condition. In the population over 18 years is a negative correlation between muscle strength and body composition variables and cardiovascular risk (R = -0.60 p 0.01) was observed, and aerobic power equally between these variables (R = -0.428 p 0.01). CONCLUSION: Although anthropometric measurements in children under 18 are generally below the limits of risk for cardiovascular disease, these results are close to those limits, which leads to argue that they need a specific prevention program. In itself a relationship between risk variables and qualities as strength and aerobic capacity is observed, so it is necessary to create programs that encourage the practice of physical activity in this population.