Prevent the zoonosis in the families of San Roque Community, Sucre Canton, Manabí.This investigation is experimental, and transversal.The survey were applied to 40 families and were determined the following variables, characteristics and sociodemografic, risk factors, knowledge and practices.School level of mothers, elementary 50%, high school 29%and university 12%, fertile age of pregnant ,mothers, elementary 50%, high school 29% and university 12%, fertile age of pregnant mothers 70% ; risk factors, illnesses, toxoplasmosis children in contact with cats 98%; Histoplasmosis, manure of birds 61%; Rabia, animals 70%.We suggest that applying a better sanitary education, having the animals outside home, and ask for help to the Ministery of Heath for a better handle of domestic animals.