The investigation is for the expertise of entrepreneurial studies and entrepreneurship, from which explains the correlation between the process of formation, maintenance and stabilization of business units and elements that encourage the entrepreneurial spirit and drive to entrepreneurship in Santa Marta. Elected commune III as a case study, being a sector that traditionally develop productive activities that by their nature can throw business information relevant to our research topic. With the survey to give an approximation of the entrepreneurial process in Santa Marta, from a descriptive research and exploratory, which developed around the following question: What are the forms of entrepreneurship and creation of production units in Santa Marta those we to identify the dynamics and principles of entrepreneurship at the local level?