Acute lymphocytic leukemia (ALL) is the most common cancer in children; approximately 30% of the malignant tumors in children are acute leukemia, and 75% of them are ALL.In Colombia, the incidence rate (IR) for pediatric cancer and for acute leukemia is 141.2 and 60.1/per year/million people, in children younger than 15 years, respectively.There are approximately 2000 new pediatric cancer cases every year, and 800 of those are ALL [1].By having the goal of reducing mortality and improving the chances for early diagnosis and treatment for children affected by this condition, the Science Technology and Innovation Government Office (COLCIENCIAS), in conjunction with the Ministry of Health, promoted the development of Clinical Practice Guidelines (CPG) for acute leukaemia in children and teenagers in order to provide recommendations regarding the management for Pediatric patients suffering from ALL and Acute Myeloid Leukaemia (AML) [2].The risk factors and early detection sections apply to all levels of the healthcare system, led by general practitioners, paediatricians and family physicians, nurses and other basic healthcare personnel.Clinical aspects of diagnosis, treatment, prognosis and monitoring apply only at the level of the centres of high complexity, having units of pediatric haematology oncology and specialized medical and infrastructure for specialized care.An important aspect in the guidelines process were patient perspective, which was considered four times during the process: prior to the formulation of recommendations for the review of the literature search of references that explore the values of patients and their families related to ALL, in generating recommendations including specific recommendations on important for patients aspects, taking into account their values and preferences in the care process of the disease in order that the professional caregiver to be aware of them and during the publication of the first draft and the final text, groups of patients