Spondylodiscitis is an infection of the vertebral body and the intervertebral disc whose initial clinical manifestations can be confused with mechanical low back pain.It is important a rapid diagnosis, and to take into account risk factors that can favor its development. Early management can prevent the disability caused by this disease.The incidence of this entity in Western society varies from 0.4 to 2.4 per 100,000 inhabitants per year, and different comorbidities increase the risk: diabetes, intravenous drug use, alcoholism, liver cirrhosis, cancer, renal failure, immunosuppression, invasive spinal procedures or infections affecting the genitourinary and gastrointestinal system.