This article presents preliminary advances in the human paleodietary characterization of individuals from the Antofagasta de la Sierra, puna de Catamarca (Northwestern Argentina) micro-region. Samples belong to individuals from different agro-pastoral periods from the Late Holocene. A methodology based on stable isotope analysis (δ13C collagen y δ15N; δ13C apatite) was applied to a total of 14 individuals, taking into consideration local and neighboring resources. Results indicate that in most cases consumption of C4 vegetable species like maize (Zea mays) and amaranth (Amaranthus caudatus) was less relevant vis-à-vis other resources, while meat resources from lower elevations of the Puna eco-region were of higher importance https://doi.org/10.22380/2539472X44