Cerebral palsy (CP) is a motor disorder of central origin with a heterogeneouspresentation, which is attributed multiple risk factors; but in fact its etiology is little known. New advances in genetics as exome and genomic sequencing have allowed to be closer to the genetic associations with the PC. It have been found the involvement of genetic factors that appear to be predisposing and in other cases, mutations in genes that can be potentially pathogenic, also associated with other neurological disorders. Understanding the underlying genetic factors in the presentation of the PC; it have allowed reevaluate the concepts that exists about the PC as well as the possibility of a better classification of this, which enables routing the therapeutic alternatives with a greater certainty. Nevertheless there is still needs to know the causal role in the PC. Genetic research becomes an important tool in patients with PC, especially after exhausting other diagnostic tools and continuous lack of knowledgeof its etiology.