The performance of the photovoltaics systems depends on the weather, specifically on the irradiance and temperature, features that reveal a 99 % of the system performance. The design of the photovoltaic system depends on the veracity, for this reason it is significant to put photovoltaics panels in different locations. This research shows an analysis on the influence and efficiency of irradiance and temperature in different locations in the central region of Colombia. The characterization of the solar energy potential (irradiance) is done in four locations of the central region of Colombia where different environmental conditions can be found, likewise it is intended to do a characterization of the ambient temperature of each place that affects the panel, and finally do a characterization of the panel efficiency under the irradiance and temperature conditions of the four places already set. Curves IV and PV were built for the three panels in each location, there were 743 measurements in total, an average of 62 measurements in each city. The systematization, analysis and results show efficiencies that allow us to classify the places and analyze the irradiance and temperature within the output of the power panel.