Knowing the most important characteristics of patients with malformation of cleft lip and cleft palate, who were seen in the city of Cali, at Fundacion Gracias a Dios un Nino Sonrie, since 2007 to 2014, allows a better care plan for these patients, not only within the Foundation, but also in the public health sector, responsible for caring pregnant women and children in their early stages of growth and development. The study is conducted in a specific population that has intervened surgical and integrally and allows describe sociodemographic variables and risk factors associated pathology, highlighting in sociodemographic variables: ethnicity, age, gender, and family and toxicological background. Important similarities and some differences from other studies on this subject were found.