To evaluate the effectiveness of three different strategies for training in the use of WHO Safe Childbirth Checklist (SCC) in Colombia health institutions to improve neonatal and maternal patient safety. Quasi-experimental before and after study. Three training programs were designed and implemented in three facilities for implementing of the use of WHO SCC. Random assignation to the intervention was performed. The safety behaviors were assessed in the four moments of the attention (on admission, just before pushing or caesarean, soon after birth and before discharge) on 29 births per institution, and the acceptance of the checklists was assessed in 38 workers of the institution A, 74 of the institution B and 50 of …