Colombia is a fragmented country, difficult to understand as a homogeneous whole. Each natural region into which it is divided has its own characteristics. One of these regions is Antioquia, where, for various reasons, a distinct group of people exist with marked differences from the rest of the population. Anthropologists, historians, sociologists, and economists have written countless interpretations of El caso antioqueño (The Antioquia Case). One of the pioneering works is by the American geographer James Parsons, who, in 1948, as part of his PhD written at the University of Berkeley, California, wrote the classic study La colonización antioqueña en el occidente colombiano (The Antioquian Colonization in Western Colombia). In the words of the researcher Alejandro Reyes, in this book the American geographer “se concentró en el problema de explicar cómo un grupo regional se distinguió y acumuló tantos recursos morales e intelectuales, cómo su cultura perfiló una ética basada en el trabajo familiar y el ahorro que permitieron hacer de Antioquia la región industrial y emprendedora que la distingue en Colombia” (focused on the problem of explaining how a regional group located and accumulated so many moral and intellectual resources, and how its culture outlined an ethic based on family labor and savings that led to the making of Antioquia as the industrial and entrepreneurial region that stands out in Colombia) (Reyes 1986:199). This chapter proposes to provide a description of the cultural evolution of this region's society during the second half of the nineteenth century and the early twentieth century.