To the Editor: Alfonso Quijano, the main character of the novel Don Quijote de la Mancha, is a madman who pursues a goal all of his own that others think of as futile.1 Sisyphus, another hero of sorts, was condemned to the useless effort of eternally pushing a rock to the top of a hill only to see it roll down over and over again.2 In contrast, Bellerophon, grandson of Sisyphus, became famous for a more goal-oriented and arguably more useful achievement; he hunted down and killed the Chimera (a frightful mythological monster whose body was composed of parts of several different animals).3 Albert Camus wrote that even the most apparently useless activity might instead be directed toward high-level objectives that bear fruit in the long term and become a reason for inner satisfaction.2 As illustrated in the Thomas Cole's painting "The Voyage of Life," the boat that the voyager guides modifies its destiny according to changes in the landscape. That today large portions of the population get to grow old is a huge achievement that comes with a great responsibility of care and protection. Ergo, as geriatricians, we have clearly stated that older adults should receive care that is unique and holistic, which has strongly distinguished our approach from those of other specialties. Clearly defined entities already exist that characterize the targets of beneficial interventions for older adults (e.g., disability, falls, delirium, depressive symptoms, quality of life).4-6 Geriatricians have left a strong imprint on each of these examples by optimally describing stand-alone and accurately defined conditions. Yet, in geriatrics, there are a number of chimeras, a mishmash of entities, perhaps as a result of difficulty understanding and defining geriatric problems; by forgetting the original call to pursue a career in older adult care, some professionals give birth to hybrids that mimic what other specialties commonly do with their "stand-alone disease approach." Using chimeras is, for geriatricians, a flawed way of revealing new paradigms. Creating chimeras is not different from Sisyphus's task; researchers can easily add new and different pieces over and over again, only to be forced to begin anew each time. In this context, it is by no means trivial the attention that has been granted to the "p-hacking" problem. Chasing the chimeras in the different databases without a clear hypothesis while waiting for the longed-for "P < .05" to make its appearance does not help in the battle for survival in geriatrics. Attributing a new name to a well-established negative condition is not a guarantee of novelty or clinical or research relevance. For example, we have long known that the physical and cognitive domains of the older individual are closely related. Do we need to develop new ways of stating this? Do we need to operationalize conditions as "cognitive frailty" or "osteosarcopenia" to reinforce once more the association between the two? The urge to give a new name to something known for decades in geriatrics may simply indicate a weakness in spreading our ideas and evidence. Instead of generating further evidence, we make a name change in the false hope that the message will get through. We strive to obtain easy and immediate success by generating a chimera that will simply create confusion and misunderstandings, although every geriatrician knows (or should know) that chimeras are clinically irrelevant; they will not change geriatric practice and are conducive to a nihilism of sorts in our discipline: if everything goes, nothing really matters. Nihilism is a philosophical doctrine that denies the existence of several aspects of life.7 For a nihilist, it is worthless to pursue anything if the result will not change. The lack of respect that the discipline of geriatrics has endured might be justified if geriatricians start chasing these mythological monsters, if they take up this kind of chimeric nihilism and forget the real tasks they are called for. Some lucidity as to what the objective of our discipline should be is in order. It is pivotal to advance in the practical care of older adults without looking for vague, artificial, and contentious definitions that add nothing to what we already know. Quoting Nietzsche, "When nihilism prevails in some disciplines, these will change their values and progress into a better future."7 Conflict of Interest: The editor in chief has reviewed the conflict of interest checklist provided by the authors and has determined that the authors have no financial or any other kind of personal conflicts with this paper. Author Contributions: Sánchez-Garrido wrote the manuscript and gave substantial ideas of the text. Cesari improved the manuscript, gave substantial ideas, and supervised all stages of the manuscript writing. Sgaravatti, Zengarini, Moreira, Borda, Zúñiga-Gil gave substantial ideas for the manuscript. Pérez-Zepeda had the original idea and coordinated all stages of the manuscript writing. Sponsor's Role: None.