Massive hemoptysis is a challenge in the patient with neoplastic lung disease due to its high mortality and the demand of a multidisciplinary approach. Its management entails intensive care, interventional pulmonology, hemodynamics, radiology and surgery. We present the case of a patient with obstructive endobronchial lesions and severe hemoptysis diagnosed as metastatic gestational choriocarcinoma, who was successfully treated with endoscopic intervention and chemotherapy.