The flux of CO2 was estimated between the atmosphere and the Colombian Pacific Ocean derived using data by satellite (Sea Surface Temperature, wind speed) between 2000 and 2011 and validated with in situ data available at the Carbon Dioxide Infor­mation and Analysis Center. Thus, it was identified that the Co­lombian Pacific has a tendency to capture CO2. The average flux for the time period studied ranged between -20 and -25 mmol/ /day, except for the months of June 2009 and 2010. The data va­lidation was performed by reference November 2010, showing better performance for November data (=0,58 ; RMSE=37%). So the trend of CO2 flux estimation from satellite data showed a ten­dency to underestimate the flux data (BIAS = -14 %). Finally , the statistical analysis indicated that while validating satellite data flux vs. the in situ showed a good performance as a preliminary tool for estimating the fluxes, it is concluded that it is necessary to have greater amounts of data on site, this for the purpose of adjusting and improving the estimation model.