The implementation of remote access laboratories by universities is a growing tendency. Worldwide its implementation has been carried out in different disciplines using different technologies, interfaces and protocols. In this sense, it is logical to conclude that there is no fixed methodology or standard for its implementation, which leads researchers to question its effectiveness and differentiation for learning purposes during lab work. It is equally necessary to mention the importance of using collaborative and immersive environment tools to perform lab exercises with remote access since they complement its use and application. In this chapter, is presented the contributions by the implementation of collaborative and immersive environments in the development of laboratory with remote access from the point of view of its effectiveness and differentiation in learning.