The volatile components from the fresh leaves of Gynoxys meridana Cuatrec. were obtained by hydrodistillation and analyzed by GC/MS. A total of 25 compounds, representing 99.3% of the oil, were identified. The dominant compounds were γ-curcumene (31.9%), fukinanolide (22.3%), β-pinene (9.5%), α-phellandrene (7.1%) and α-pinene (5.7%).