The characteristics of the slaughterhouse effluents and current wastewater treatment practices in the province of Ontario, Canada are analyzed. Meat processing plants are found to produce large amounts of wastewater due to the slaughtering process and cleaning of their facilities. Furthermore, the composition of the wastewater varies according to the type and number of animals slaughtered and the water requirements of the process. However, the slaughterhouse wastewater usually contains high levels of organics and nutrients. Several slaughterhouses in Ontario discharge their wastewater into the municipal sewer system after primary pretreatment at the meat processing plant. Therefore, due to the high-strength characteristics of the slaughterhouse effluents, an extensive treatment for a safe discharge into the environment is required. Thus, the combination of biological processes and advanced oxidation technologies for slaughterhouse wastewater treatment is evaluated in this study. Results show that the application of combined biological and advanced oxidation processes is recommended for on-site slaughterhouse wastewater treatment.