Celiac Disease (CD) is a rare autoimmune disorder with manifestations at different levels including the central nervous system. The disease develops as a consequence of intolerance to gluten on individuals with genetic susceptibility. It originates as a result of the interaction between genetic and environmental factors, on individuals predisposed, through a faulty immune system response to prolamin derived peptides. Usually the diagnosis is established based on clinical suspicion, either within a suspicious family group context or in patients with suggestive manifestations of this disease.