Dengue is currently the most important viral disease transmitted by arthropods and which is hyperendemic in the Americas. An increase in the number of cases is related to dengue during pregnancy and the neonatal period. According to the gestational age in which infection occurs, there could be different manifestations in the fetus including abortion, malformations or neonatal dengue in newborns.This article presents a review regarding some cases reported worldwide, especially in the Americas,and some pathophysiologic issues related to perinatal dengue. doi: http://dx.doi.org/10.7705/biomedica.v33i0.1449