The Nursing Process Problem (NPP) has the main objective of defining the nursing diagnosis based on the initial patient diagnosis, his/her medical history and the classifications of NANDA, NIC and NOC nomenclatures. The main objective is to propose the characterization of NPP, where the health initial conditions and the medical history of patients can be treated through the assignment of interventions nurses who must comply with the objectives of nurses. We present an AIMMS simulation for The NPP problem using CPLEX technique for solving NPP instances to generate a staff nurse assignation.