Objective:The aim of this study was to compare the results of the semen analysis data while applying the parameters set out in the previous standard and the last proposed, in order to assess the changes in the diagnosis in terms of normal or abnormal, as how this fact can affect treatment decisions.Methods: 1184 semen analysis of patients undergoing examination at our institution were reviewed, between January 2010 and September 2012 and were classified as normal or abnormal according to WHO parameters of 1999 and 2010 to be then compared.Exams of patients over 50 years (39 cases) were excluded for having found in this group a significant increase of asthenozoospermia when compared to younger ages.Results: In the 1145 semen analysis studied, the averadifference was found while analyzing the absolute seminal variables of volume, motility and sperm morphology in the different age groups.Semen parameters in the 1999 were reported as normal with the WHO 2010 compa-ver, the sperm morphology according to the WHO 2010, Conclusion: Based in our data, the sperm analysis as a single tool in the diagnosis of male factor should be revaluated.