This paper studied, through an experiment design, the significance of particle size, air speed and reactor arrangement for palm shell micro-gasification process in order to optimize the heating value of the syngas obtained. The range of variables was 8 to 13 mm for particle size, 0.8–1.4m/s for air velocity, and updraft or downdraft for the reactor type. It was found that the particle size and air velocity factors were the most significant in the optimization of the output variable, syngas heating value. A heating value of 2.69MJ / Nm3 was obtained using a fixed bed downdraft reactor, with a particle size of 13 mm and 1.4 m/s for air speed; verification of the optimum point of operation under these conditions verified that these operating conditions favor the production of a gas with a high energy value.