Heart activity monitoring is an important task for prevention and treatment of cardiovascular diseases. However, development of long-term, wearable electrodes remains an open issue. In fact, adhesion ability and energy consumption while preserving aesthetics is one of the major concerns to implement a minimally invasive monitoring system that measures and transmits electrocardiographic signals (ECG) during long-term periods of time. Based on the concepts of functionality, wearability, and resources, we develop a new long-term ECG monitoring system under the wear-and-forget principle. We also propose a system model of the electrode-skin interface that performs real-time measurements with a minimally invasive effect when compared with another competitive and implantable systems. As a result, testing of designed prototype shows that the developed very long-term ECG monitoring patch improves energy consumption and adhesion time up to 40 days.