Isolated and Marginalized Communities (CMA) in Latin America, and particularly in the Andes, have some characteristics that generate the need to design policies to improve their living conditions. In order to define their situation, this paper relied on primary and secondary sources of information are defined and quantified the CMA in the three Andean countries. Then basic demographic data of the CMA compared with national averages are presented. In all cases similar indicators are reported among CMA but substantially different when compared with national averages, always above.