Guatemala is a country of considerable cultural diversity. Among the more than twenty Mayan groups that populate its territory, the Poqomchi' who inhabit Alta and Baja Verapaz have preserved a great deal of their particular idiosyncrasy inherited from the ancient Maya. The main purpose of this article is to analyze the most important aspects of Poqomchi' spirituality and religiosity as the legacy of the ancient Maya from whom they descend, as well as a product both of their constant interaction with other Mayan groups and syncretism as a survival mechanism. For this purpose, it is based on systematic participant observation and interviews which have led to conclude that the main features of Poqomchi' spirituality remain alive even today, although not free from the influence of the peoples with whom they share space.