Introduction: a batch study was carried out for the adsorption of Pb (II) and Ni (II) in binary solution using biomasses from corncob and orange peel.Methods: the initial concentrations of each metal were varied in 25, 50, 75 and 100 ppm. The adsorption was conducted at pH 6.0 and biomass size of 0.5 mm. Measurements of residual metal concentrations were determined by atomic absorption.Results: it was found that the initial metal concentration and binary solutions not interfere with the removal percentage of the contaminants, and the Freundlich and Langmuir models provided a good fit of the experimental data.Conclusion: it was also established that the metal antagonistic action changes according to the biomass used, being the capacity of Ni (II)>Pb (II) for the corncob biomass, and Pb (II)> Ni (II) for the orange peels.