Curriculum renewal in higher education is a necessary process for the Universities. For achieving new ways of educative design are required dynamic and innovative processes. Such educative design should respond to the actual society changes. Nowadays, one of the main trends to address the curricula design process is the competences-based design and the active learningbased design, searching to locate the students in the center of the learning process. At the Engineering Faculty of Universidad de Medellín the curricula innovation process for the undergraduate programs is being developed. This process is supported by the innovation in the didactic cycle in terms of methodologies, strategies, and techniques for active learning. The curriculum innovation proposal from the area of Basic Science of Engineering (CBI) is presented in this paper. This area is located between Basic Sciences and Applied Engineering in the curriculum structure of the programs from Engineering Faculty. Our proposal of the curriculum innovation is being developed by using Design-Science research methodology and aligned with fundamentals and principles of the CDIO initiative. In this paper we present the following preliminary results: the CBI training core in based in competences, a set of relevant strategies and techniques for active learning in CBI, and the alignment with the CDIO learning goals.