Abstract Faith and Trueman [Syst. Biol. (2001) 331] recently proposed “Profile Parsimony” (PP) as a new form of phylogenetic analysis, but it is equivalent to the Implied Weights (IW) method when certain functions are used. The PP method cannot accommodate missing/inapplicable cells and/or multistate characters. Finally we demonstrate that, as defined, PP scores are not random, and there is no need to generate random trees as proposed by Faith and Trueman.