An alternative is presented in this paper to improve the performance in a supply chain (CS), when introducing the so-called centralized supply chain. This implies a global management based on the CONWIP-proceeding system. A simulation model was designed to explore and evaluate the comparative advantages of this strategy in front the performance of the fully integrated supply chain (CS TI). The analysis is carried out for different levels of variability in demand and with possible materials-flow restrictions along the chain. This research can show the advantages and improved performance that this centralization system actually has in the global metrics whenever both strategies are offering similar levels of service. Its main advantages are: 1. A lower impact from the variability in demand on the ordering policies, and 2. Lower levels of average finished-goods and work in process (FGI+WIP) levels.