The study of psychosocial risk factors regains more relevance to the dynamics imposed by globalized economies that generate competitive environments, increasing the physical, psychological and social needs of workers who manifest different answers as chronic job stress also known as Burnout or Syndrome of burning for Work (SQT).This study aimed to determine the prevalence of burnout and its relationship with the presence of occupational psychosocial risk factors, perceived as negative in workers of the Economically Active Population (EAP) in Lima, Peru.339 workers were surveyed with the implementation of Inventory General Survey (MBI-GS) 1 , instrument in its new version, and the scale of Psychosocial Factors in Work 2 , finding high prevalence of burnout in the dimension emotional exhaustion (6,22% ), associated with 4 different psychosocial risk factors, the biggest risk factor is represented by work demands (p <0,004) and (OR = 6,979) with the cynicism of burnout dimension, the previous makes it clear that with work demands, workers expressed cynicism as a defense mechanism, so it is concluded that the prevalence of burnout was significantly related to psychosocial risk factors, hence that organizations should pay special attention to these factors.