ADVERTISEMENT RETURN TO ISSUEPREVReviewNEXTStructural and Immunological Principles Leading to Chemically Synthesized, Multiantigenic, Multistage, Minimal Subunit-Based Vaccine DevelopmentManuel Elkin Patarroyo*‡§, Adriana Bermúdez‡∥, and Manuel Alfonso Patarroyo‡∥View Author Information‡ Fundación Instituto de Inmunología de Colombia (FIDIC), Carrera 50, No. 26-00, Bogotá, Colombia§ Universidad Nacional de Colombia∥ Universidad del Rosario*Phone number: +57-14815219. Fax number: +57-1-4815269. E-mail: [email protected]Cite this: Chem. Rev. 2011, 111, 5, 3459–3507Publication Date (Web):March 25, 2011Publication History Received15 July 2010Published online25 March 2011Published inissue 11 May 2011https://pubs.acs.org/doi/10.1021/cr100223mhttps://doi.org/10.1021/cr100223mreview-articleACS PublicationsCopyright © 2011 American Chemical SocietyRequest reuse permissionsArticle Views4659Altmetric-Citations71LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Biopolymers,Immunology,Molecules,Peptides and proteins,Vaccination Get e-Alerts