The research presented in this article examines women's perceptions of how the criminal laws relating to prostitution affect the experience of working in the off-street Canadian sex industry. The results of interviews with 10 women indicate that the criminalization of prostitution has numerous effects on the health and safety of indoor workers: the workers are alienated from the protective services of police; they are often misinformed about their legal rights in Canada; they face personal, legal, and social consequences for association with a criminalized activity; their abilities to mitigate risk are severely limited by the criminalization of ancillary activities related to prostitution; and their health is directly affected by the isolation and stress that accompany marginalized labour. The participants share their advice for future regulation of the sex industry in Canada and strongly encourage the removal of adult consensual sex work from the realm of criminal behaviour in Canada.