In a changing world, both socially and economically, the university reflects upon its research work.Social responsibility and the demand for knowledge of the means of production require a significant contribution from university research.In response to this situation, the university explores models to manage the knowledge produced by research.This study explores the conditions for implementing a university knowledge management model.It concludes that in a possible interface university/external sector, the university must first recognize its own internal conditions: technologies, research, organizational forms, interaction and communication, so as to properly design an interface with the external sector and, in this way, to manage the knowledge it produces.