ABSTRACT In this paper we report a facile and efficient procedure for the synthesis of 1,3,5-tris-arylhexahydro-1,3,5-triazines (3) by reaction of anilines 1 with 1,3,6,8-tetrazatricyclo[4.4.1.1[3] Kauffman, W.J. 1975. J. Heterocyclic Chem., : 409[Crossref] , [Google Scholar], [8a] Jones, R.A.Y., Katritzky, A.R. and Snarey, M. 1967. J. Chem. Soc. B, : 387 [Google Scholar], [8b] Florentine, R.A. and Miller, J.G. 1959. J. Am. Chem. Soc., 81: 5103[Crossref] , [Google Scholar]- dodecane (TATD) (2). The diequatorial chair conformational preference of 3b (Ar = p-tolyl) in the solid state was established by X-ray crystallography and agrees well with molecular mechanics calculations.
Tópico:
Synthesis and Characterization of Heterocyclic Compounds
